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NHS plans to DNA test all babies in England to assess disease risk

Posted on June 21, 2025 By Admin No Comments on NHS plans to DNA test all babies in England to assess disease risk


Every newborn baby in England will have their DNA mapped to assess their risk of hundreds of diseases, under NHS plans for the next 10 years.

The scheme, first reported by the Daily Telegraph, is part of a government drive towards predicting and preventing illness, which will also see £650m invested in DNA research for all patients by 2030.

Health Secretary Wes Streeting said gene technology would enable the health service to “leapfrog disease, so we’re in front of it rather than reacting to it”.

It comes after a study analysing the genetic code of up to 100,000 babies was announced in October.

The government’s 10-year plan for the NHS, which is set to be revealed over the coming few weeks, is aimed at easing pressure on services.

The Department for Health and Social Care said that genomics – the study of genes – and AI would be used to “revolutionise prevention” and provide faster diagnoses and an “early warning signal for disease”.

Screening newborn babies for rare diseases will involve sequencing their complete DNA using blood samples from their umbilical cord, taken shortly after birth.

There are approximately 7,000 single-gene disorders. The NHS study which began in October only looked for gene disorders that develop in early childhood and for which there are effective treatments.

Currently, newborn babies are offered a heelprick blood test that checks for nine serious conditions, including cystic fibrosis.

The health secretary said in a statement: “With the power of this new technology, patients will be able to receive personalised healthcare to prevent ill-health before symptoms begin, reducing the pressure on NHS services and helping people live longer, healthier lives.”

Streeting added: “The revolution in medical science means that we can transform the NHS over the coming decade, from a service which diagnoses and treats ill-health to one that predicts and prevents it.”

Sequencing DNA gives a lot of information about a person which can then be used to make predictions about the likelihood of them having particular genetic diseases, according to Prof Robin Lovell-Badge, a geneticist at the Francis Crick Institute.

These include conditions like muscular dystrophy, liver diseases and some kidney problems, he told BBC Radio 4’s Today programme.

Funding for the new initiative will also support efforts by Genomics England to build one of the world’s largest research databases, with the goal of containing over 500,000 genomes by 2030.

It builds on work the NHS carried out in recent months, in which it embarked on a study to track the entire genetic code of up to 100,000 newborn babies in England to screen for genetic conditions.

But Prof Lovell-Badge cautioned that the government would not only need to hire people to collect the data, but qualified professions who could interpret it for patients.

“You need people to have conversations with individuals who might be affected by genetic disease,” he said, adding that “one of the things that worries me” was an insufficient number of genetic counsellors.

“It’s not just having the information, it’s conveying the information in an appropriate, helpful way.”



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