{"id":814,"date":"2023-11-15T15:43:53","date_gmt":"2023-11-15T15:43:53","guid":{"rendered":"https:\/\/ventil.rs\/blog\/health\/v-a-recruits-millionth-veteran-for-its-genetic-research-database\/"},"modified":"2023-11-15T15:43:53","modified_gmt":"2023-11-15T15:43:53","slug":"v-a-recruits-millionth-veteran-for-its-genetic-research-database","status":"publish","type":"post","link":"https:\/\/ventil.rs\/blog\/health\/v-a-recruits-millionth-veteran-for-its-genetic-research-database\/","title":{"rendered":"V.A. Recruits Millionth Veteran for Its Genetic Research Database"},"content":{"rendered":"<p> <br \/>\n<\/p>\n<div>\n<h2 class=\"css-1usjan8 e12nqm5i0\" id=\"link-4e05669d\"><span>A Moment That Sums It Up: 3:46 p.m.<\/span><\/h2>\n<p class=\"css-at9mc1 evys1bk0\">The millionth vet joined the database on the afternoon of Nov. 11. Employees who had waited a dozen years for this moment wept.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">As the goal approached, the department had started an intensive email campaign, encouraging vets to sign up online or at V.A. medical centers. In the few weeks building up to the millionth vet, what had been a few hundred enrollees a day turned into thousands. The department created a ticker, which it posted online, showing the numbers.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cThis is a gift to the world,\u201d said Denis McDonough, secretary of veterans affairs.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The V.A. will continue to enroll more vets to the database, but this was a symbolic moment.<\/p>\n<h2 class=\"css-1usjan8 e12nqm5i0\" id=\"link-b02190f\"><span>Why It Matters: A diverse database yields disease insights.<\/span><\/h2>\n<p class=\"css-at9mc1 evys1bk0\">For years, researchers have been building large databases for genetic research. Using them they have found, for example, genes that appear to confer resistance to dementia and ones that most likely contribute to obesity. The discoveries provide paths to understanding these diseases and developing treatments.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">There are other large genetic databases, but they have mostly been built in Europe and include few minorities. The V.A. says its database offers a more diverse population: 175,000 people with African ancestry and 80,000 Hispanics joined the Million Veteran Program. The database also includes 100,000 women.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cIt\u2019s a massive investment and scientific opportunity,\u201d said Dr. Amit V. Khera, a genetic researcher at Massachusetts General Hospital. He is not a V.A. researcher, but he has used the data through collaborations with researchers who are affiliated with the department.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">As the database acquired participants, about 600 V.A. researchers registered to use it. The result so far has been more than 350 papers on diseases and disorders, including post-traumatic stress disorder, heart disease, high blood pressure and nonalcoholic liver disease.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">For example, said Dr. Sumitra Muralidhar, director of the Million Veteran Program, researchers found <a class=\"css-yywogo\" href=\"https:\/\/www.nature.com\/articles\/s41593-019-0447-7\" title=\"\" rel=\"noopener noreferrer\" target=\"_blank\">genes linked to having flashbacks of traumatic events<\/a>, a feature of post-traumatic stress. Now, Dr. Muralidhar said, investigators can study those genes and the role they play, which may help in developing treatments for PTSD.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">The department also says it is being mindful of patient privacy. Although researchers can examine genetic and other data and links to medical records, fewer than 10 people at the V.A. have the links that tie records to individuals. Those records, Dr. Muralidhar said, are held at a facility in Boston that is \u201cheavily secured.\u201d<\/p>\n<h2 class=\"css-1usjan8 e12nqm5i0\" id=\"link-d75c176\"><span>What It Looks Like: Veterans hope the database will help.<\/span><\/h2>\n<p class=\"css-at9mc1 evys1bk0\">In 2019, a nurse at a V.A. hospital told Octavia Harris, 60, of San Antonio, about the Million Veteran Program. She signed up and said participating was a chance to help other vets and to help herself.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">Ms. Harris, who retired from the Navy in 2012 after 30 years of service, said three conditions run in her family \u2014 diabetes, high blood pressure and arthritis. She is hoping that with her genetic and health information added to that of so many others, researchers will make useful discoveries.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">In her family, Ms. Harris said, people died young.<\/p>\n<p class=\"css-at9mc1 evys1bk0\">\u201cWe haven\u2019t lived beyond the age of 70,\u201d she said. \u201cI want to go past 70.\u201d<\/p>\n<\/div>\n<p><br \/>\n<br \/><a href=\"https:\/\/www.nytimes.com\/2023\/11\/15\/health\/million-veterans-database-va.html\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>A Moment That Sums It Up: 3:46 p.m. The millionth vet joined the database on the afternoon of Nov. 11. Employees who had waited a dozen years for this moment wept. As the goal approached, the department had started an intensive email campaign, encouraging vets to sign up online or at V.A. medical centers. In&#8230;<\/p>\n<p class=\"more-link-wrap\"><a href=\"https:\/\/ventil.rs\/blog\/health\/v-a-recruits-millionth-veteran-for-its-genetic-research-database\/\" class=\"more-link\">Read More<span class=\"screen-reader-text\"> &ldquo;V.A. Recruits Millionth Veteran for Its Genetic Research Database&rdquo;<\/span> &raquo;<\/a><\/p>\n","protected":false},"author":1,"featured_media":815,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"fifu_image_url":"https:\/\/static01.nyt.com\/images\/2023\/11\/15\/science\/15million-vets\/15million-vets-facebookJumbo.jpg","fifu_image_alt":"","footnotes":""},"categories":[4],"tags":[],"class_list":["post-814","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-health"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v17.8 (Yoast SEO v22.1) - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>V.A. 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